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비쥬얼

Brief description of products

Using natural Scottish flora and with the support of Scottish herbalists,
we produce of a wide range of active natural cosmetic ingredients that effectively improve the skin through anti-aging,
skin brightening and more. Our highly acclaimed products include…

컨텐츠

Product

Great Mullein Extract
INCI name: Verbascum Thapsus Extract
Great Mullein is a biennial that is native to the UK. During its first year of growth cycle it produces oval leaves with grey hairs in a
rosette shape. In the second year it produces a flower spike with many small yellow flowers in late summer.
Scottish folk tales have shown mullein was widely used in various forms to treat various conditions. Dried mullein leaves were used
to treat respiratory problems such as coughs and asthma. While the flowers were drunk as a tea or were used to dye both hair and
linen a golden colour. Powdered mullein was used to treat gout while an infusion of mullein flowers in a carrier oil could treat
earache. Distilled flower water was also used to treat skin conditions.
In modern cosmetic applications great mullein extract is used as a skin conditioning agent. Our own research has shown great
mullein has good antioxidant results. 

 


Figure 1: 



figure 01.png


-Nearly 50% scavenging activity achieved at 1.3% extract concentration 


-Almost 100% scavenging achieved at 5.0% extract concentration, optimal activity is achieved by 5.0% concentration 


-Antioxidant activity confirmed 


 


Figure 2: 



figure 02.png


Reactive Oxygen Species (ROS) such as peroxides, superoxide, hydroxyl radical and singlet oxygen cause damage to cells through
inflammation and oxidation 


- HDFn (normal human dermal fibroblast) cells were treated with Mullein extract and without Mullein extract to serve as negative
control 


- ROS levels were measured using DCFH-DA assay 


- Dichlorofluorescein (DCF) is a highly fluorescent compound which can be detected by fluorescence spectroscopy 


- Decrease in fluorescence intensity indicates reduction in the generation of ROS
0.5%, 1% and 2% extract concentrations showed nearly equal effects but significant decrease in ROS generation compared to
control 


 -Although small differences, trend shows decrease in ROS generation with increase in extract concentration from 0.5% to 2.0% 


 - Antioxidant properties of Great Mullein extract is confirmed